Ajay K Gopal Selected Research

procaine isothiocyanate (PRIT)

12/2020	Therapy of Myeloid Leukemia using Novel Bispecific Fusion Proteins Targeting CD45 and 90Y-DOTA.
1/2018	CD38-bispecific antibody pretargeted radioimmunotherapy for multiple myeloma and other B-cell malignancies.
11/2016	Comparative Analysis of Bispecific Antibody and Streptavidin-Targeted Radioimmunotherapy for B-cell Cancers.
1/2015	Comparative efficacy of 177Lu and 90Y for anti-CD20 pretargeted radioimmunotherapy in murine lymphoma xenograft models.
2/2014	A preclinical model of CD38-pretargeted radioimmunotherapy for plasma cell malignancies.
12/2011	Pretargeted radioimmunotherapy using genetically engineered antibody-streptavidin fusion proteins for treatment of non-hodgkin lymphoma.
7/2011	Anti-CD45 pretargeted radioimmunotherapy using bismuth-213: high rates of complete remission and long-term survival in a mouse myeloid leukemia xenograft model.
11/2010	Conventional and pretargeted radioimmunotherapy using bismuth-213 to target and treat non-Hodgkin lymphomas expressing CD20: a preclinical model toward optimal consolidation therapy to eradicate minimal residual disease.
8/2009	Pretargeting CD45 enhances the selective delivery of radiation to hematolymphoid tissues in nonhuman primates.
1/2009	Pretargeted radioimmunotherapy using anti-CD45 monoclonal antibodies to deliver radiation to murine hematolymphoid tissues and human myeloid leukemia.

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Ajay K Gopal Research Topics

Disease

49	Lymphoma (Lymphomas) 12/2022 - 05/2002
44	Neoplasms (Cancer) 01/2022 - 05/2002
35	Non-Hodgkin Lymphoma (Lymphosarcoma) 01/2022 - 10/2003
22	B-Cell Lymphoma (Lymphoma, B Cell) 12/2022 - 05/2004
19	Mantle-Cell Lymphoma (Lymphoma, Mantle Cell) 01/2020 - 05/2002
18	Hodgkin Disease (Hodgkin's Disease) 08/2021 - 09/2008
17	Follicular Lymphoma (Lymphoma, Small Cleaved Cell, Follicular) 01/2022 - 10/2003
13	Hematologic Neoplasms (Hematological Malignancy) 12/2021 - 05/2005
11	Diffuse Large B-Cell Lymphoma (Lymphoma, Large Cell, Diffuse) 01/2022 - 08/2014
9	Multiple Myeloma 02/2022 - 02/2014
8	B-Cell Chronic Lymphocytic Leukemia (Chronic Lymphocytic Leukemia) 12/2021 - 02/2014
8	Leukemia 12/2020 - 02/2008
7	Acute Myeloid Leukemia (Acute Myelogenous Leukemia) 12/2020 - 03/2006
4	Thrombocytopenia (Thrombopenia) 12/2022 - 01/2015
4	Myeloid Leukemia (Leukemia, Myelocytic) 12/2020 - 05/2007
4	Anaplastic Large-Cell Lymphoma (Ki 1 Lymphoma) 11/2017 - 07/2009
4	Residual Neoplasm 02/2016 - 11/2010
3	Neutropenia 12/2022 - 03/2014
3	Fatigue 01/2020 - 01/2015
3	Myelodysplastic Syndromes (Myelodysplastic Syndrome) 01/2019 - 12/2009
3	Disease Progression 01/2016 - 06/2008
2	Diarrhea 12/2021 - 03/2014
2	AIDS-Related Complex (ARC) 01/2021 - 12/2019
2	Hemorrhage 01/2019 - 05/2017
2	Graft vs Host Disease (Graft-Versus-Host Disease) 01/2019 - 01/2016
2	Burkitt Lymphoma (Burkitt's Lymphoma) 01/2017 - 01/2015
2	Pathologic Complete Response 02/2016 - 02/2015

Drug/Important Bio-Agent (IBA)

23	Rituximab (Mabthera)FDA Link 01/2021 - 05/2004
17	Brentuximab VedotinIBA 08/2021 - 06/2012
12	procaine isothiocyanate (PRIT)IBA 12/2020 - 06/2007
12	Monoclonal AntibodiesIBA 01/2020 - 05/2002
11	Etoposide (VP 16)FDA LinkGeneric 08/2021 - 05/2002
9	Proteins (Proteins, Gene)FDA Link 02/2022 - 11/2010
9	Cyclophosphamide (Cytoxan)FDA LinkGeneric 01/2020 - 05/2002
8	fludarabineIBA 01/2021 - 12/2009
8	Radioisotopes (Radionuclides)IBA 01/2021 - 11/2010
7	Chimeric Antigen ReceptorsIBA 12/2022 - 09/2008
7	Biotin (Vitamin H)FDA Link 01/2018 - 06/2007
7	StreptavidinIBA 11/2016 - 02/2008
7	Immunoconjugates (Immunoconjugate)IBA 01/2016 - 06/2007
6	Dexamethasone (Maxidex)FDA LinkGeneric 12/2022 - 04/2009
6	idelalisibIBA 12/2021 - 03/2014
6	Doxorubicin (Adriamycin)FDA LinkGeneric 01/2020 - 01/2017
6	AntibodiesIBA 08/2014 - 06/2007
4	axicabtagene ciloleucelIBA 12/2022 - 01/2018
4	Bortezomib (Velcade)FDA Link 02/2022 - 10/2015
4	Carboplatin (JM8)FDA LinkGeneric 08/2021 - 08/2010
4	Bendamustine Hydrochloride FDA Link 01/2021 - 12/2014
4	Cytarabine (Cytosar-U)FDA LinkGeneric 01/2021 - 10/2008
4	DOTA-biotin (90Y-DOTA-biotin)IBA 12/2020 - 05/2009
4	AntigensIBA 12/2019 - 06/2007
4	Prednisone (Sone)FDA LinkGeneric 01/2019 - 01/2017
4	tositumomab I-131 (Bexxar)FDA Link 01/2016 - 05/2008
3	Proteasome InhibitorsIBA 02/2022 - 10/2015
3	ibrutinibIBA 01/2022 - 10/2018
3	Biological ProductsIBA 01/2022 - 05/2004
3	IceIBA 08/2021 - 04/2013
3	Melphalan (Alkeran)FDA LinkGeneric 01/2021 - 10/2008
3	Vincristine (Oncovin)FDA LinkGeneric 01/2019 - 01/2017
3	FenretinideIBA 01/2017 - 05/2004
3	TRU 016IBA 01/2015 - 02/2014
3	HLA-DR Antigens (HLA-DR)IBA 05/2009 - 06/2007
2	L-Lactate Dehydrogenase (Lactate Dehydrogenase)IBA 12/2022 - 12/2013
2	CreatinineIBA 02/2022 - 05/2017
2	Lenalidomide (CC 5013)FDA Link 02/2022 - 01/2021
2	Agammaglobulinaemia Tyrosine KinaseIBA 01/2022 - 10/2018
2	Aspartate Aminotransferases (Aspartate Transaminase)IBA 12/2021 - 08/2021
2	Ifosfamide FDA LinkGeneric 08/2021 - 11/2018
2	Carmustine (FIVB)FDA Link 01/2021 - 10/2008
2	Biomarkers (Surrogate Marker)IBA 01/2020 - 01/2020
2	utomilumabIBA 01/2020 - 01/2018
2	Androgen Receptors (Androgen Receptor)IBA 01/2020 - 01/2017
2	Cisplatin (Platino)FDA LinkGeneric 01/2020 - 04/2009
2	Iodine-131IBA 12/2019 - 09/2014
2	Astatine-211IBA 10/2019 - 03/2015
2	Sirolimus (Rapamycin)FDA Link 01/2019 - 01/2018
2	Transaminases (Aminotransferases)IBA 01/2018 - 03/2014
2	Pharmaceutical PreparationsIBA 03/2017 - 08/2013
2	Alkylating AgentsIBA 01/2017 - 03/2014
2	RetinoidsIBA 01/2017 - 10/2015
2	Phosphotransferases (Kinase)IBA 01/2016 - 10/2015
2	ibritumomab tiuxetan (Zevalin)FDA Link 02/2015 - 07/2011
2	Indicators and Reagents (Reagents)IBA 01/2015 - 06/2007
2	Surface Antigens (Surface Antigen)IBA 05/2009 - 06/2007
2	Leukocyte Common Antigens (CD45 Antigen)IBA 01/2009 - 08/2008
2	Busulfan (Busulfex)FDA Link 10/2008 - 03/2006

Therapy/Procedure

48	Therapeutics 12/2022 - 05/2002
31	Radioimmunotherapy 11/2022 - 05/2002
22	Cell Transplantation 11/2022 - 05/2005
19	Drug Therapy (Chemotherapy) 08/2021 - 04/2008
18	Stem Cell Transplantation 08/2021 - 05/2002
9	Transplantation 01/2018 - 05/2002
8	Homologous Transplantation 11/2022 - 07/2006
5	Radiotherapy 01/2020 - 05/2009
5	Hematopoietic Stem Cell Transplantation 05/2013 - 10/2003
4	Autologous Transplantation 01/2020 - 07/2006
2	Aftercare (After-Treatment) 12/2022 - 01/2018
2	Injections 02/2022 - 12/2020
2	Immunotherapy 01/2021 - 01/2016
2	Induction Chemotherapy 02/2016 - 06/2008